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Michael Gregory

Michael Gregory

Facility Director: Michael Gregory


Michael Gregory, MS, SCYM(ASCP)CM is the Director of the Flow Cytometry Cell Sorting Facility at the California Institute of Technology (Caltech) and has twenty-plus years of experience in flow cytometry and Shared Resource Laboratories (SRLs). He holds a Bachelor of Arts in Biology and a Master of Science in Biology, both from New York University. He is certified as a Specialist in Flow Cytometry by the American Society for Clinical Pathology (ASCP). He is also a former International Society for the Advancement of Cytometry (ISAC) SRL Emerging Leader (2014-2018).

Prior to his arrival at Caltech, Michael was the Flow Cytometry Core Director at the Cleveland Clinic's Florida Research and Innovation Center. There, he established the flow cytometry core and biosafety level 3 cell sorting facility at this brand-new research center. Before Cleveland Clinic, Michael spent 12 years at the Cytometry and Cell Sorting Laboratory of the New York University Langone Medical Center where he managed the day-to-day laboratory operations as Lab Manager and then Technical Director. Michael has experience across a wide range of flow cytometry applications and instrumentation, beginning his career in an infectious disease and T-Cell immunology lab, characterizing monoclonal antibodies for therapeutic use at a cancer biotech, experiencing a vast variety of flow cytometry assay types and applications at the NYU core facility, and most recently, gaining cell sorting biosafety and viral infectious disease work at Cleveland Clinic Florida.

Michael's work with the International Society for the Advancement of Cytometry (ISAC) keeps him up to date on the newest flow cytometry technologies and applications, but also connects him to a large network of flow cytometry experts. He was involved with the publication of the 2016 ISAC Flow Cytometry SRL Best Practices and as SRL Committee Chair (2018-2024) has helped to develop the ISAC SRL Recognition Program, which recognizes flow cytometry SRLs for their excellence in adhering to these best practices, developed the SRL Standard Operating Procedure (SOP) Repository, which facilitates the sharing of SOPs between SRLs, and championed other projects to support SRLs. He is also a member of the ISAC Governance Committee, which is responsible for review and maintenance of the society's Constitution, Bylaws and Policies & Procedures.

In his role as Director of the Flow Cytometry Cell Sorting Facility at Caltech, Michael oversees the day-to-day operations of the facility and staff. He consults with new and current users of the facility to determine how best flow cytometry and cell sorting can help address their research questions. His experience with a wide range of flow cytometry applications, keen interest in experimental and technical troubleshooting, and access to a wide network of flow cytometry experts are important assets for users of the facility. Beyond the general services of the facility, he is available for advanced training in flow cytometry sample preparation and data analysis, as well as consultation regarding downstream cell-sorting applications (such as single-cell RNA-sequencing).

Member, International Society for the Advancement of Cytometry

Member, So Cal Flow Association

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